This is a compact list of the top 5 greatest March Madness upsets of all time
At the time, MSU was a favorite to win the National Championship to everyone looked at this game like a free win on the way to a National Title. However Middle Tennessee came out hot and was going into halftime leading 41-35. Carried by their 2 stars Reggie Upshaw with 21 points and teammate Giddy Potts with 19 points, Middle Tennessee coasted to a 90-81 win.
At the time, Ohio State was viewed as a serious contender to make a deep run, and most saw this matchup as a comfortable win Ohio State. However, Oral Roberts battling the entire game and forcing overtime after a clutch late shot. Led by guard Max Abmas, who scored 29 points, and Kevin Obanor, who also had 30 points, Oral Roberts pulled off the shocking 75-72 overtime victory becoming just the ninth #15 seed to defeat a #2 seed.
Saint Peters came into this game with 0 career NCAA tournament wins, and matched up again the powerhouse Kentucky it wasn't looking likely that they would get their first. However, carried by elite scoring by Doug Edert and Daryl Banks III combining for 47 points and outscoring Kentucky in overtime 14-8 and winning 85-79.
Coming into the tournament, the Knights were ranked as the smallest team with their biggest player being 6'3. Going up against the tallest player and National Player of The Year Zach Edey, Purdue was favored by around 30 points. Still, even being the smallest FDU ended up forcing 16 turnovers and holding Zach Edey to a 36% shooting and propelling their win over the #1 seed 63-58.
To this point in time, no 16 seed ever beat a #1 seed so everyone took this matchup as a free win for Virginia. After a close first half, they went on a 10-0 run in the first 2 minutes and ended up beating the National Title favorite by 20 points and dominating them 74-54.